Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine

Volume: 115, Issue: 23, Pages: 5839 - 5848
Published: Jun 5, 2018
Abstract
Oxygen-derived free radicals and related oxidants are ubiquitous and short-lived intermediates formed in aerobic organisms throughout life. These reactive species participate in redox reactions leading to oxidative modifications in biomolecules, among which proteins and lipids are preferential targets. Despite a broad array of enzymatic and nonenzymatic antioxidant systems in mammalian cells and microbes, excess oxidant formation causes...
Paper Details
Title
Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine
Published Date
Jun 5, 2018
Volume
115
Issue
23
Pages
5839 - 5848
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