Regulation of cell cycle progression by cell-cell and cell-matrix forces.
Abstract
It has long been proposed that the cell cycle is regulated by physical forces at the cell–cell and cell–extracellular matrix (ECM) interfaces1–12. However, the evolution of these forces during the cycle has never been measured in a tissue, and whether this evolution affects cell cycle progression is unknown. Here, we quantified cell–cell tension and cell–ECM traction throughout the complete cycle of a large cell population in a growing...
Paper Details
Title
Regulation of cell cycle progression by cell-cell and cell-matrix forces.
Published Date
May 25, 2018
Journal
Volume
20
Issue
6
Pages
646 - 654
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History