Related donor transplants: has posttransplantation cyclophosphamide nullified the detrimental effect of HLA mismatch?
Abstract
We sought to identify whether posttransplantation cyclophosphamide (PT-Cy) reduces or eliminates the detrimental impact of HLA mismatching on outcomes of HLA-haploidentical related donor transplantation for acute leukemia. Data from 2143 donor-recipient pairs (n = 218 haploidentical sibling; n = 218 offspring; n = 1707 HLA-matched sibling) with acute myeloid or lymphoblastic leukemia were studied. All received a calcineurin inhibitor for...
Paper Details
Title
Related donor transplants: has posttransplantation cyclophosphamide nullified the detrimental effect of HLA mismatch?
Published Date
May 24, 2018
Journal
Volume
2
Issue
11
Pages
1180 - 1186
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