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Lifetime Smoking History and Risk of Lung Cancer: Results From the Framingham Heart Study.

Published on May 16, 2018in Journal of the National Cancer Institute10.21
· DOI :10.1093/jnci/djy041
Hilary A. Tindle26
Estimated H-index: 26
(VUMC: Vanderbilt University Medical Center),
Meredith S. Duncan4
Estimated H-index: 4
(BU: Boston University)
+ 3 AuthorsMatthew S. Freiberg28
Estimated H-index: 28
(VUMC: Vanderbilt University Medical Center)
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  • References (35)
  • Citations (4)
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References35
Newest
Nichole T. Tanner15
Estimated H-index: 15
,
Neeti M. Kanodra3
Estimated H-index: 3
+ 5 AuthorsGerard A. Silvestri48
Estimated H-index: 48
Rationale: Smoking is the largest contributor to lung cancer risk, and those who continue to smoke after diagnosis have a worse survival. Screening for lung cancer with low-dose computed tomography (LDCT) reduces mortality in high-risk individuals. Smoking cessation is an essential component of a high-quality screening program.Objectives: To quantify the effects of smoking history and abstinence on mortality in high-risk individuals who participated in the NLST (National Lung Screening Trial).Me...
Published on Nov 1, 2015in Tumori1.23
Giulia Carreras10
Estimated H-index: 10
,
F Pistelli4
Estimated H-index: 4
(National Research Council)
+ 4 AuthorsGiuseppe Gorini16
Estimated H-index: 16
AbSTRACT Aims and background: The aims of this paper are to compute the risks of dying of ischemic heart disease (IHD), lung cancer (LC), stroke, and chronic obstructive pulmonary disease (COPD) for Italian smokers by gender, age and daily number of cigarettes smoked, and to estimate the benefit of stopping smoking in terms of risk reduction.Methods: Life tables by sex and smoking status were computed for each smoking-related disease based on Italian smoking data, and risk charts with 10-year pr...
Published on Sep 1, 2015in Journal of Medical Screening2.13
Paul F. Pinsky44
Estimated H-index: 44
,
Claire Zhu9
Estimated H-index: 9
,
Barnett S. Kramer56
Estimated H-index: 56
ObjectiveCurrent United States recommendations for low-dose computed tomography (LDCT) lung cancer screening limit eligibility to ever-smokers with 30+ pack-years, with former smokers eligible only within 15 years of quitting. The 15 year limit is partly based on perceived decreases in lung cancer risk as years since quitting (YSQ) increase. We examine the relationship between lung cancer risk and YSQ among 30+ pack-year former smokers.MethodsIn the Prostate, Lung, Colorectal, and Ovarian trial,...
Published on May 28, 2015in The New England Journal of Medicine70.67
Joseph L. Chin47
Estimated H-index: 47
,
Tamara Syrek Jensen1
Estimated H-index: 1
+ 3 AuthorsPatrick H. Conway32
Estimated H-index: 32
Thanks to recent evidence that screening with low-dose computed tomography reduces lung-cancer mortality, at-risk U.S. patients 55 to 77 years of age are now eligible for a screening benefit under Medicare, while further data are collected and assessed.
Published on Jan 1, 2015in Carcinogenesis4.00
Catherine A. Wassenaar6
Estimated H-index: 6
(U of T: University of Toronto),
Yuanqing Ye35
Estimated H-index: 35
(University of Texas MD Anderson Cancer Center)
+ 6 AuthorsRachel F. Tyndale8
Estimated H-index: 8
(U of T: University of Toronto)
We investigated genetic variation in CYP2A6 in relation to lung cancer risk among African American smokers, a high-risk population. Previously, we found that CYP2A6, a nicotine/nitrosamine metabolism gene, was associated with lung cancer risk in European Americans, but smoking habits, lung cancer risk and CYP2A6 gene variants differ significantly between European and African ancestry populations. Herein, African American ever-smokers, drawn from two independent lung cancer case–control studies, ...
Published on Dec 2, 2014in PLOS Medicine
Martin Tammemagi20
Estimated H-index: 20
(Brock University),
Timothy R. Church62
Estimated H-index: 62
(UMN: University of Minnesota)
+ 5 AuthorsChristine D. Berg56
Estimated H-index: 56
(Johns Hopkins University)
Background Lung cancer risks at which individuals should be screened with computed tomography (CT) for lung cancer are undecided. This study's objectives are to identify a risk threshold for selecting individuals for screening, to compare its efficiency with the U.S. Preventive Services Task Force (USPSTF) criteria for identifying screenees, and to determine whether never-smokers should be screened. Lung cancer risks are compared between smokers aged 55–64 and ≥65–80 y. Methods and Findings Appl...
Published on Mar 4, 2014in Annals of Internal Medicine19.32
Virginia A. Moyer56
Estimated H-index: 56
DESCRIPTION: Update of the 2004 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for lung cancer. METHODS: The USPSTF reviewed the evidence on the efficacy of low-dose computed tomography, chest radiography, and sputum cytologic evaluation for lung cancer screening in asymptomatic persons who are at average or high risk for lung cancer (current or former smokers) and the benefits and harms of these screening tests and of surgical resection of early-stage non-small cell lu...
Published on Sep 17, 2013in Annals of Internal Medicine19.32
Linda Humphrey31
Estimated H-index: 31
(OHSU: Oregon Health & Science University),
Mark Deffebach8
Estimated H-index: 8
(OHSU: Oregon Health & Science University)
+ 6 AuthorsChristopher G. Slatore24
Estimated H-index: 24
(OHSU: Oregon Health & Science University)
Data Synthesis: Four trials reported results of LDCT screening among patients with smoking exposure. One large good-quality trial reported that screening was associated with significant reductions in lung cancer (20%) and all-cause (6.7%) mortality. Three small European trials showed no benefit of screening. Harms included radiation exposure, overdiagnosis, and a high rate of falsepositive findings that typically were resolved with further imaging. Smoking cessation was not affected. Incidental ...
Published on Jul 18, 2013in The New England Journal of Medicine70.67
Stephanie Kovalchik12
Estimated H-index: 12
,
Martin Tammemagi20
Estimated H-index: 20
+ 6 AuthorsHormuzd A. Katki38
Estimated H-index: 38
Background In the National Lung Screening Trial (NLST), screening with low-dose computed tomography (CT) resulted in a 20% reduction in lung-cancer mortality among participants between the ages of 55 and 74 years with a minimum of 30 pack-years of smoking and no more than 15 years since quitting. It is not known whether the benefits and potential harms of such screening vary according to lung-cancer risk. Methods We assessed the variation in efficacy, the number of false positive results, and th...
Cited By4
Newest
Published on Sep 14, 2019in Journal of Radioanalytical and Nuclear Chemistry1.19
Pasquale Avino24
Estimated H-index: 24
(UNIMOL: University of Molise),
Alberto Rosada10
Estimated H-index: 10
(ENEA),
Maurizio Manigrasso14
Estimated H-index: 14
Nowadays, e-cigarettes are largely used, they are considered less dangerous than the traditional cigarettes. Actually, there are a lot of investigations on the health effects of nanoparticles and smoke emitted by them whereas there are very few studies on the e-liquid composition. For the first time this paper would like to investigate the inorganic composition of the e-liquids at different nicotine content (0, 9 and 18 mg mL−1) by means of the instrumental nuclear activation analysis. More than...
Published on Sep 1, 2019in European Heart Journal23.24
Patrizio Lancellotti75
Estimated H-index: 75
(University of Liège),
Patrick Marechal1
Estimated H-index: 1
(University of Liège)
+ 1 AuthorsCécile Oury16
Estimated H-index: 16
(University of Liège)
Published on Aug 20, 2019in JAMA51.27
Meredith S. Duncan4
Estimated H-index: 4
(Vandy: Vanderbilt University),
Matthew S. Freiberg28
Estimated H-index: 28
(VUMC: Vanderbilt University Medical Center)
+ 3 AuthorsHilary A. Tindle26
Estimated H-index: 26
(VUMC: Vanderbilt University Medical Center)
Importance The time course of cardiovascular disease (CVD) risk after smoking cessation is unclear. Risk calculators consider former smokers to be at risk for only 5 years. Objective To evaluate the association between years since quitting smoking and incident CVD. Design, Setting, and Participants Retrospective analysis of prospectively collected data from Framingham Heart Study participants without baseline CVD (original cohort: attending their fourth examination in 1954-1958; offspring cohort...
Published on Apr 17, 2019
Clare Fiala3
Estimated H-index: 3
(MSH: Mount Sinai Hospital, Toronto),
Jennifer Taher6
Estimated H-index: 6
(U of T: University of Toronto),
Eleftherios P. Diamandis97
Estimated H-index: 97
(U of T: University of Toronto)
Background: The term P4 medicine (predictive, preventative, personalized, participatory) was coined by Dr. Leroy Hood of the Institute for Systems Biology to demonstrate his framework to detect and prevent disease through extensive biomarker testing, close monitoring, deep statistical analysis, and patient health coaching. Methods: In 2017, this group published the results of their “100 Person Wellness Project.” They performed whole genome sequencing and 218 clinical laboratory tests, measured 6...
Published on Jun 3, 2019in Nutrition & Dietetics1.34
Tianying Wu (SDSU: San Diego State University), Samantha Sonoda (Cincinnati Children's Hospital Medical Center), Hongxia Liu (Beijing University of Chinese Medicine)
Published on Apr 26, 2019in bioRxiv
Timothy V. Pyrkov7
Estimated H-index: 7
,
Konstantin Avchaciov1
Estimated H-index: 1
+ 3 AuthorsPeter O. Fedichev8
Estimated H-index: 8
ABSTRACT We analyzed aging trajectories of complete blood counts (CBC) and their association with the incidence of chronic diseases and death in cohorts of aging individuals registered in the UK Biobank and National Health and Nutrition Examination Survey (NHANES) studies. Application of a pro-portional hazards model to the CBC data allowed us to identify the log-transformed hazard ratio as a natural biomarker of aging, which we have named the dynamic morbidity index (DMI). DMI increased with ag...
Published on Apr 1, 2019in Cancer Epidemiology2.62
Leandro Fórnias Machado de Rezende (USP: University of São Paulo), Dong-Hoon Lee32
Estimated H-index: 32
(Harvard University)
+ 3 AuthorsJosé Eluf-Neto34
Estimated H-index: 34
(USP: University of São Paulo)
Abstract Background Lifestyle risk factors (tobacco smoking, alcohol consumption, overweight and obesity, unhealthy diet, and lack of physical activity) have been associated with increased risk of at least 20 types of cancer. We estimated the proportion of cancer cases and deaths that could be potentially avoided by eliminating or reducing lifestyle risk factors in Brazil. Methods We obtained the distribution of lifestyle risk factors by sex and age groups from recent representative health surve...
Published on Nov 1, 2018in Journal of the National Cancer Institute10.21
Erin E. Hahn6
Estimated H-index: 6
(KP: Kaiser Permanente),
Michael K. Gould23
Estimated H-index: 23
(KP: Kaiser Permanente)
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