Disruptive innovation in acute stroke systems of care

Alteplase is the only drug approved by the US Food and Drug Administration (FDA) and the European Medical Agency to be used before endovascular thrombectomy for ischaemic stroke. Now, Campbell and colleagues 1 Campbell BCV Mitchell PJ Churilov L et al. Tenecteplase versus alteplase before thrombectomy for ischemic stroke. N Engl J Med. 2018; 378: 1573-1582 Crossref PubMed Scopus (363) Google Scholar showed evidence of a convincing alternative to...