Testicular toxicity and reproductive performance of streptozotocin-induced diabetic male rats: the ameliorating role of silymarin as an antioxidant

Diabetes mellitus (DM) is a glucose, fat, and protein metabolism disorder. Testicular toxicity and reproductive dysfunction are consequences of streptozotocin (STZ)-induced diabetes. Oxidative stress has been suggested as one of the main mechanism involved in STZ-induced toxicity. Since many studies revealed that Silymarin (SMN), a plant extract, has anti-diabetic and antioxidant activity, this study was conducted to evaluate the effects of this...