An 18-mo randomized, double-blind, placebo-controlled trial of DHA-rich fish oil to prevent age-related cognitive decline in cognitively normal older adults

Fish oil trials in cognitively healthy older adults have yielded inconsistent results. Supplementation may differentially affect the domains that underpin cognitive performance, and effects may differ across sex or genotype. The aim of this study was to test whether docosahexaenoic acid (DHA)–rich fish oil slows 18-mo cognitive decline in cognitively healthy elders. In a double-blind, randomized, placebo-controlled, parallel-group trial,...