Validation study of genetic biomarkers of response to TNF inhibitors in rheumatoid arthritis
Abstract
Genetic biomarkers are sought to personalize treatment of patients with rheumatoid arthritis (RA), given their variable response to TNF inhibitors (TNFi). However, no genetic biomaker is yet sufficiently validated. Here, we report a validation study of 18 previously reported genetic biomarkers, including 11 from GWAS of response to TNFi. The validation was attempted in 581 patients with RA that had not been treated with biologic antirheumatic...
Paper Details
Title
Validation study of genetic biomarkers of response to TNF inhibitors in rheumatoid arthritis
Published Date
May 7, 2018
Journal
Volume
13
Issue
5
Pages
e0196793 - e0196793
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