Formulation design of hydroxypropyl cellulose films for use as orally disintegrating dosage forms

Hydroxypropyl cellulose (HPC) is a water-soluble polymer used as a binder during pharmaceutical tableting and granulation. HPC is also known as a base material for pharmaceutical film by virtue of its film formability with excellent plasticity. The aim of this study was to assess the applicability of HPC to orally disintegrating film (ODF) and to investigate optimization of the ODF formulation of HPC. The effects of the molecular weight of HPC...