Flavonoids and saponins from two Bulgarian Astragalus species and their neuroprotective activity
Abstract
Two novel compounds from A. glycyphylloides DC (1–2) and three rare flavonoids from A. spruneri Boiss. (3–5), alongside their neuroprotective activity and possible effects as human monoamine oxidase type B inhibitors were reported. The structural elucidation of the compounds was achieved by chemical, HRESIMS and NMR analyses. Their effects were investigated in vitro on isolated rat brain synaptosomes in 6-hydroxydopamine-induced toxicity. In...
Paper Details
Title
Flavonoids and saponins from two Bulgarian Astragalus species and their neuroprotective activity
Published Date
Aug 1, 2018
Journal
Volume
26
Pages
44 - 49
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