Match!

“In-Group” Communication in Marine Vibrio: A Review of N-Acyl Homoserine Lactones-Driven Quorum Sensing

Published on May 7, 2018in Frontiers in Cellular and Infection Microbiology3.52
· DOI :10.3389/fcimb.2018.00139
Jianfei Liu2
Estimated H-index: 2
,
Kaifei Fu3
Estimated H-index: 3
+ 3 AuthorsLijun Zhou3
Estimated H-index: 3
Cite
Abstract
N-Acyl Homoserine Lactones (N-AHLs) are an important group of small quorum-sensing molecules generated and released into the surroundings by Gram-negative bacteria. N-AHLs play a crucial role in various infection-related biological processes of marine Vibrio species, including survival, colonization, invasion and pathogenesis. With the increasing problem of antibiotic abuse and subsequently the emergence of drug-resistant bacteria, studies on AHLs are therefore expected to bring potential new breakthroughs for the prevention and treatment of Vibrio infections. This article starts from AHLs generation in marine Vibrio, and then discusses the advantages, disadvantages, and trends in the future development of various detection methods for AHLs characterization. In addition to a detailed classification of the various marine Vibrio-derived AHL types that have been reported over the years, the regulatory mechanisms of AHLs and their roles in marine Vibrio biofilms, pathogenicity and interaction with host cells are also highlighted. Intervention measures for AHLs in different stages are systematically reviewed, and the prospects of their future development and application are examined.
  • References (134)
  • Citations (4)
Cite
References134
Newest
Published on Oct 1, 2017in Journal of Bacteriology3.23
Alyssa S. Ball1
Estimated H-index: 1
(IU: Indiana University Bloomington),
Ryan R. Chaparian2
Estimated H-index: 2
(IU: Indiana University Bloomington),
Julia C. van Kessel10
Estimated H-index: 10
(IU: Indiana University Bloomington)
Published on Apr 20, 2017in Sensors3.03
Léa Girard2
Estimated H-index: 2
,
Elodie Blanchet6
Estimated H-index: 6
+ 5 AuthorsRaphaël Lami10
Estimated H-index: 10
Since the discovery of quorum sensing (QS) in the 1970s, many studies have demonstrated that Vibrio species coordinate activities such as biofilm formation, virulence, pathogenesis, and bioluminescence, through a large group of molecules called N-acyl homoserine lactones (AHLs). However, despite the extensive knowledge on the involved molecules and the biological processes controlled by QS in a few selected Vibrio strains, less is known about the overall diversity of AHLs produced by a broader r...
Published on Apr 1, 2017in Applied Microbiology and Biotechnology3.67
Shanshan Zhang2
Estimated H-index: 2
(NBU: Ningbo University),
Ningning Liu3
Estimated H-index: 3
(NBU: Ningbo University)
+ 3 AuthorsChenghua Li8
Estimated H-index: 8
(NBU: Ningbo University)
In the present study, the effects of an environmental friendly natural reagent coumarin, on the growth and potential virulence factors, as well as its ability to interfere the infection of Vibrio splendidus (Vs), were determined. Coumarin showed no effects on the maximal growth of Vs, and biofilm formation of Vs, while it significantly decreased protease activity and hemolytic activity by 43 and 80%, respectively. Correspondingly, coumarin exhibited an obviously protective effect, with a relativ...
Published on Jan 1, 2017in Cell36.22
Thomas M. Bartlett1
Estimated H-index: 1
(Princeton University),
Benjamin P. Bratton9
Estimated H-index: 9
(Princeton University)
+ 11 AuthorsMichael S. VanNieuwenhze23
Estimated H-index: 23
(IU: Indiana University Bloomington)
Summary Pathogenic Vibrio cholerae remains a major human health concern. V. cholerae has a characteristic curved rod morphology, with a longer outer face and a shorter inner face. The mechanism and function of this curvature were previously unknown. Here, we identify and characterize CrvA, the first curvature determinant in V. cholerae . CrvA self-assembles into filaments at the inner face of cell curvature. Unlike traditional cytoskeletons, CrvA localizes to the periplasm and thus can be consid...
Published on Sep 1, 2016in Journal of Food Science and Technology-mysore1.85
Jamuna Bai Aswathanarayan5
Estimated H-index: 5
(University of Mysore),
V. Ravishankar Rai14
Estimated H-index: 14
(University of Mysore)
Quorum sensing or cell to cell communication which includes inter- and intra-cellular communication has been implicated in the production of virulence factor and formation of biofilm in food-borne pathogens. In the present study, the effect of quorum sensing signals on the biofilms of food-borne pathogens has been elucidated. N-butryl homoserine lactone and N-hexanoyl homoserine lactone belonging to acyl homoserine lactone (AHL) family of signaling molecules were investigated for their effect on...
Published on Aug 1, 2016in Food Microbiology4.09
Sara Elmahdi2
Estimated H-index: 2
(UMES: University of Maryland Eastern Shore),
L DaSilva4
Estimated H-index: 4
(UMES: University of Maryland Eastern Shore),
Salina Parveen17
Estimated H-index: 17
(UMES: University of Maryland Eastern Shore)
Vibrio parahaemolyticus and Vibrio vulnificus are the leading causes of seafood associated infections and mortality in the United States. The main syndromes caused by these pathogens are gastroenteritis, wound infections, and septicemia. This article reviewed the antibiotic resistance profile of V. parahaemolyticus and V. vulnificus in the United States and other countries including Italy, Brazil, Philippines, Malaysia, Thailand, China, India, Iran, South Africa and Australia. The awareness of a...
Published on Jun 3, 2016in Journal of Biomolecular Structure & Dynamics3.31
Sundaraj Rajamanikandan5
Estimated H-index: 5
(Alagappa University),
Jeyaraman Jeyakanthan15
Estimated H-index: 15
(Alagappa University),
Pappu Srinivasan11
Estimated H-index: 11
(Alagappa University)
Master quorum sensing (QS) regulator LuxR of Vibrio harveyi is a unique member of the TetR protein superfamily. Recent studies have demonstrated the contribution of thiazolidinedione analogues in blocking QS by decreasing the DNA-binding ability of LuxR. However, the precise mechanism of thiazolidinedione analogues binding to LuxR is still unclear. In the present study, molecular docking combined with molecular dynamics (MD) simulations was performed to understand the mechanism of ligand binding...
Published on Apr 2, 2016in Journal of Aquatic Animal Health0.92
Weihua Chu2
Estimated H-index: 2
(CPU: China Pharmaceutical University),
Robert J. C. McLean31
Estimated H-index: 31
(Texas State University)
AbstractQuorum sensing (QS) is a process of bacterial communication used to control group behaviors, including bioluminescence, virulence factor production, biofilm formation, and biofilm antimicrobial tolerance. Many aquatic bacterial pathogens such as Aeromonas, Vibrio, and Edwardsiella spp. use QS to regulate virulence factor production. The disruption of QS has been shown to be an effective strategy in the competition between higher organisms and bacteria and more recently between bacterial ...
Published on Dec 1, 2015in Current Microbiology1.59
Jeyan S. Kumar1
Estimated H-index: 1
(University of Mysore),
S. Umesha13
Estimated H-index: 13
(University of Mysore)
+ 1 AuthorsP. Niranjana1
Estimated H-index: 1
(Kuvempu University)
Many bacteria use small diffusible signaling molecules to communicate each other termed as quorum sensing (QS). Most Gram-negative bacteria use acyl homoserine lactone (AHL) as QS signal molecules. Using these signaling molecules, bacteria are able to express specific genes in response to population density. This work aimed to detect the production of QS signal molecules and biofilm formation in Ralstonia solanacearum isolated from various diseased tomato plants with symptoms of bacterial wilt. ...
Published on Nov 1, 2015in Journal of Microbiological Methods1.80
James C. Charlesworth5
Estimated H-index: 5
(UNSW: University of New South Wales),
Önder Kimyon7
Estimated H-index: 7
(UNSW: University of New South Wales)
+ 1 AuthorsBrendan P. Burns30
Estimated H-index: 30
(UNSW: University of New South Wales)
Many microorganisms use quorum sensing to regulate several complex phenotypes, and this is accomplished by the release of a signal molecule(s) into the environment. N-acyl-homoserine lactones (AHLs) are a common class of signalling molecule utilized by a range of microorganisms (primarily Gram negative bacteria but most recently also archaea) and are often detected through the use of bacterial biosensors. Biosensors can be limited by both their specificity and sensitivity, and the aim of this st...
Cited By4
Newest
Published on Apr 9, 2019in bioRxiv
Daniela Prasse7
Estimated H-index: 7
(CAU: University of Kiel),
Nancy Weiland-Braeuer1
Estimated H-index: 1
(CAU: University of Kiel)
+ 2 AuthorsRuth Schmitz-Streit1
Estimated H-index: 1
(CAU: University of Kiel)
The associated microbiota of marine invertebrates plays an important role to the host in relation to fitness, health and homeostasis of the metaorganism. As one key chemically-mediated interaction, Quorum sensing (QS) and interference with QS among colonizing bacteria ultimately affects the establishment and dynamics of the microbial community on the host. Aiming to address interspecies competition of cultivable microbes associated to merging model species of the basal animal phyla Cnidaria ( Au...
Published on Mar 25, 2019in Marine Drugs3.77
Marta Torres3
Estimated H-index: 3
,
Yves Dessaux35
Estimated H-index: 35
,
Inmaculada Llamas18
Estimated H-index: 18
Saline environments, such as marine and hypersaline habitats, are widely distributed around the world. They include sea waters, saline lakes, solar salterns, or hypersaline soils. The bacteria that live in these habitats produce and develop unique bioactive molecules and physiological pathways to cope with the stress conditions generated by these environments. They have been described to produce compounds with properties that differ from those found in non-saline habitats. In the last decades, t...
Published on Jan 1, 2019in Microbial Biotechnology
Agnieszka Sekowska23
Estimated H-index: 23
,
Hiroki Ashida15
Estimated H-index: 15
(Kobe University),
Antoine Danchin68
Estimated H-index: 68
View next paperQUORUM SENSING IN PLANT-ASSOCIATED BACTERIA