An InDel in Phospholipase-C-B-1 Is Linked with Euthyroid Multinodular Goiter
Abstract
Euthyroid multinodular goiter (MNG) is common, but little is known about the genetic variations conferring predisposition. Previously, a family with MNG of adolescent onset was reported in which some family members developed papillary thyroid carcinomas (PTC).Genome-wide linkage analysis and next-generation sequencing were conducted to identify genetic variants that may confer disease predisposition. A multipoint nonparametric LOD score of 3.01...
Paper Details
Title
An InDel in Phospholipase-C-B-1 Is Linked with Euthyroid Multinodular Goiter
Published Date
Jul 1, 2018
Journal
Volume
28
Issue
7
Pages
891 - 901
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