White matter tract network disruption explains reduced conscientiousness in multiple sclerosis
Abstract
Quantifying white matter (WM) tract disruption in people with multiple sclerosis (PwMS) provides a novel means for investigating the relationship between defective network connectivity and clinical markers. PwMS exhibit perturbations in personality, where decreased Conscientiousness is particularly prominent. This trait deficit influences disease trajectory and functional outcomes such as work capacity. We aimed to identify patterns of WM tract...
Paper Details
Title
White matter tract network disruption explains reduced conscientiousness in multiple sclerosis
Published Date
May 8, 2018
Journal
Volume
39
Issue
9
Pages
3682 - 3690
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