Acute hematological and mood perception effects of bitter orange extract (p- synephrine) consumed alone and in combination with caffeine: A placebo-controlled, double-blind study

The purpose of this study was to examine acute hematological and mood perception responses to supplementation with p ‐synephrine alone and in combination with caffeine during quiet sitting. Sixteen subjects visited the laboratory on 6 occasions and were given (in randomized double‐blind manner) 103‐mg p‐ synephrine (S), 233‐mg caffeine + 104‐mg p ‐synephrine, 240‐mg caffeine, 337‐mg caffeine + 46‐mg p ‐synephrine, 325‐mg caffeine, or a placebo...