Impact of knee joint loading exercise on MRI-assessed articular cartilage in people at risk of, or with established, knee osteoarthritis: a systematic review of randomized controlled trials

Purpose: To investigate the impact of knee joint loading exercise on articular cartilage in people at risk of, or with established, knee osteoarthritis (OA) by conducting a systematic review of randomized controlled trials (RCT). Methods: A systematic literature search was performed in the databases MEDLINE, EMBASE, CINAHL,the Cochrane Central Register of Controlled Trials (CENTRAL) and Web of Science up to September 2017, with no restriction on...