Replication study of polymorphisms associated with response to methotrexate in patients with rheumatoid arthritis
Abstract
About 70 genetic studies have already addressed the need of biomarkers to predict the response of patients with rheumatoid arthritis (RA) to methotrexate (MTX) treatment. However, no genetic biomarker has yet been sufficiently validated. Here, we aimed to replicate a selection of 25 SNPs in the largest collection of patients up to date, which consisted of 915 patients treated with MTX. The change in disease activity (measured as ΔDAS28) from...
Paper Details
Title
Replication study of polymorphisms associated with response to methotrexate in patients with rheumatoid arthritis
Published Date
May 9, 2018
Journal
Volume
8
Issue
1
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