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Is genome-guided cancer treatment hyped?

Published on Apr 27, 2018in Science41.04
· DOI :10.1126/science.360.6387.365
Jocelyn Kaiser32
Estimated H-index: 32
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Abstract
For people with advanced cancer who are running out of options, many cancer centers now offer this hope: Have your tumor9s genome sequenced, and doctors will match you with a drug that targets its weak spot. But this booming area of cancer treatment has critics, who say its promise has been oversold. Last week, two prominent voices in the field faced off in a sometimes-tense debate on what9s often called precision oncology at the annual meeting of the American Association for Cancer Research in Chicago, Illinois. Their dispute threw a splash of cold water on a meeting packed with sessions on genome-based cancer treatments.
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Published on Apr 17, 2019
Clare Fiala3
Estimated H-index: 3
(MSH: Mount Sinai Hospital, Toronto),
Jennifer Taher6
Estimated H-index: 6
(U of T: University of Toronto),
Eleftherios P. Diamandis97
Estimated H-index: 97
(U of T: University of Toronto)
Background: The term P4 medicine (predictive, preventative, personalized, participatory) was coined by Dr. Leroy Hood of the Institute for Systems Biology to demonstrate his framework to detect and prevent disease through extensive biomarker testing, close monitoring, deep statistical analysis, and patient health coaching. Methods: In 2017, this group published the results of their “100 Person Wellness Project.” They performed whole genome sequencing and 218 clinical laboratory tests, measured 6...
Published on Apr 8, 2019in Experimental Biology and Medicine3.00
Ajaikumar B. Kunnumakkara14
Estimated H-index: 14
(IITG: Indian Institute of Technology Guwahati),
Devivasha Bordoloi10
Estimated H-index: 10
(IITG: Indian Institute of Technology Guwahati)
+ 6 AuthorsBharat B. Aggarwal150
Estimated H-index: 150
Although better science and technology has been linked with better health care, however, reality is much different. Although America and most of Europe are equipped with most advanced science and t...
Published on Feb 1, 2019in Nuclear Medicine and Molecular Imaging
Dong Soo Lee57
Estimated H-index: 57
,
Gi Jeong21
Estimated H-index: 21
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