Polygenic Risk Scores, School Achievement, and Risk for Schizophrenia: A Danish Population-Based Study

Studies have suggested that poor school achievement is associated with increased risk of schizophrenia; however, the possible genetic contribution to this association is unknown. We investigated the possible effect of the polygenic risk score (PRS) for schizophrenia (PRSSCZ) and for educational attainment (PRSEDU) on the association between school performance and later schizophrenia.We conducted a case-cohort study on a Danish population-based...