Ability of Polyphosphate and Nucleic Acids to Trigger Blood Clotting: Some Observations and Caveats
Abstract
Polyphosphate plays several roles in coagulation and inflammation, while extracellular DNA and RNA are implicated in thrombosis and as disease biomarkers. We sought to compare the procoagulant activities of polyphosphate versus DNA or RNA isolated from mammalian cells. In a recent study, we found that much of the procoagulant activity of DNA isolated from mammalian cells using Qiagen kits resisted digestion with nuclease or polyphosphatase, and...
Paper Details
Title
Ability of Polyphosphate and Nucleic Acids to Trigger Blood Clotting: Some Observations and Caveats
Published Date
Apr 17, 2018
Journal
Volume
5
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History