A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency
Abstract
Defects in the respiratory chain, interfering with energy production in the cell, are major underlying causes of mitochondrial diseases. In spite of this, the surprising variety of clinical symptoms, disparity between ages of onset, as well as the involvement of mitochondrial impairment in ageing and age-related diseases continue to challenge our understanding of the pathogenic processes. This complexity can be in part attributed to the unique...
Paper Details
Title
A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency
Published Date
May 14, 2018
Journal
Volume
245
Issue
3
Pages
311 - 323
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