Total Synthesis and Biological Evaluation of Phaeosphaerides
Abstract
This article reviews studies regarding the total synthesis of phaeosphaerides A and B, nitrogen-containing bicyclic natural products isolated from an endophytic fungus. Numerous synthetic efforts and an X-ray crystal structure analysis of phaeosphaeride A have enabled revision of its originally proposed structure. In addition, a successful protic acid-mediated transformation of phaeosphaeride A to phaeosphaeride B revealed the hypothetical...
Paper Details
Title
Total Synthesis and Biological Evaluation of Phaeosphaerides
Published Date
May 14, 2018
Journal
Volume
8
Issue
5
Pages
206 - 206
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