QSOX1 regulates trophoblastic apoptosis in preeclampsia through hydrogen peroxide production
Volume: 32, Issue: 22, Pages: 3708 - 3715
Published: Sep 6, 2018
Abstract
Objective: Oxidative stress plays a significant role in the pathogenesis of preeclampsia (PE), by inducing trophoblast cell death and consequent placental dysfunction. Quiescin sulfhydryl oxidase 1 (QSOX1) is upregulated in many types of cancer cells; it promotes disulfide bond formation as well as hydrogen peroxide (H2O2) production. The aims of present study are to investigate the expression pattern of QSOX1 in placentae of pregnancies...
Paper Details
Title
QSOX1 regulates trophoblastic apoptosis in preeclampsia through hydrogen peroxide production
Published Date
Sep 6, 2018
Volume
32
Issue
22
Pages
3708 - 3715
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