Coronary computed tomographic angiography findings and their therapeutic implications in asymptomatic patients with familial hypercholesterolemia. Lessons from the SAFEHEART study

•Familial hypercholesterolemia (FH) is associated with premature atherosclerosis. •Coronary artery involvement is highly prevalent in asymptomatic patients with FH. •Severity of coronary involvement is associated with estimated cardiovascular risk. •Knowledge of the coronary involvement might induce an improvement in management. Background Familial hypercholesterolemia (FH) confers an increased risk of premature atherosclerotic disease. Coronary...