2-Arachidonoylglycerol: A signaling lipid with manifold actions in the brain
Abstract
2-Arachidonoylglycerol (2-AG) is a signaling lipid in the central nervous system that is a key regulator of neurotransmitter release. 2-AG is an endocannabinoid that activates the cannabinoid CB1 receptor. It is involved in a wide array of (patho)physiological functions, such as emotion, cognition, energy balance, pain sensation and neuroinflammation. In this review, we describe the biosynthetic and metabolic pathways of 2-AG and how chemical...
Paper Details
Title
2-Arachidonoylglycerol: A signaling lipid with manifold actions in the brain
Published Date
Jul 1, 2018
Journal
Volume
71
Pages
1 - 17
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