Translational genomics in pancreatic ductal adenocarcinoma: A review with re-analysis of TCGA dataset
Abstract
Malignancy of the pancreas is a leading cause of cancer-related mortality, with the highest case-fatality of all cancers. Nevertheless, the lack of sensitive biomarkers and presence of biological heterogeneity precludes its early detection and effective treatment. The recent introduction of next-generation sequencing allows characterization of multiple driver mutations at genome- and exome-wide levels. Sequencing of DNA and RNA from circulating...
Paper Details
Title
Translational genomics in pancreatic ductal adenocarcinoma: A review with re-analysis of TCGA dataset
Published Date
Apr 1, 2019
Journal
Volume
55
Pages
70 - 77
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Notes
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