Poly(GP), neurofilament and grey matter deficits in C9orf72 expansion carriers
Volume: 5, Issue: 5, Pages: 583 - 597
Published: Apr 6, 2018
Abstract
Objective To evaluate poly( GP ), a dipeptide repeat protein, and neurofilament light chain (NfL) as biomarkers in presymptomatic C9orf72 repeat expansion carriers and patients with C9orf72‐ associated frontotemporal dementia. Additionally, to investigate the relationship of poly( GP ) with indicators of neurodegeneration as measured by NfL and grey matter volume. Methods We measured poly( GP ) and NfL levels in cerebrospinal fluid ( CSF ) from...
Paper Details
Title
Poly(GP), neurofilament and grey matter deficits in C9orf72 expansion carriers
Published Date
Apr 6, 2018
Volume
5
Issue
5
Pages
583 - 597
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