T222. Functional Brain Activation and Grey Matter Integrity in Psychosis: A Combined Functional Magnetic Resonance and Neurite Orientation Distribution and Density Imaging Study
Abstract
Post-mortem studies in psychosis consistently find reduced dendritic spine density and length, which are thought to underlie deficits in neural activation and cognitive function. Using task-fMRI and neurite orientation dispersion and density imaging (NODDI), we tested the hypothesis that 1) brain activity in a distributed prefrontal-parietal network during working memory would be reduced in psychosis; 2) regions demonstrating reduced activation...
Paper Details
Title
T222. Functional Brain Activation and Grey Matter Integrity in Psychosis: A Combined Functional Magnetic Resonance and Neurite Orientation Distribution and Density Imaging Study
Published Date
May 1, 2018
Journal
Volume
83
Issue
9
Pages
S214 - S215
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