Glucocorticoid-Induced Metabolic Disturbances Are Exacerbated in Obese Male Mice
Abstract
The purpose of this study was to determine the effects of glucocorticoid-induced metabolic dysfunction in the presence of diet-induced obesity. C57BL/6J adult male lean and diet-induced obese mice were given dexamethasone, and levels of hepatic steatosis, insulin resistance, and lipolysis were determined. Obese mice given dexamethasone had significant, synergistic effects on fasting glucose, insulin resistance, and markers of lipolysis, as well...
Paper Details
Title
Glucocorticoid-Induced Metabolic Disturbances Are Exacerbated in Obese Male Mice
Published Date
Apr 11, 2018
Journal
Volume
159
Issue
6
Pages
2275 - 2287
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