Contraction of basal filopodia controls periodic feather branching via Notch and FGF signaling
Abstract
Branching morphogenesis is a general mechanism that increases the surface area of an organ. In chicken feathers, the flat epithelial sheath at the base of the follicle is transformed into periodic branches. How exactly the keratinocytes are organized into this pattern remains unclear. Here we show that in the feather follicle, the pre-branch basal keratinocytes have extensive filopodia, which contract and smooth out after branching. Manipulating...
Paper Details
Title
Contraction of basal filopodia controls periodic feather branching via Notch and FGF signaling
Published Date
Apr 9, 2018
Journal
Volume
9
Issue
1
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