Effect of resveratrol on doxorubicin resistance in breast neoplasm cells by modulating PI3K/Akt signaling pathway

In the study, we probed into the effect of Resveratrol (RES) on Doxorubicin (DOX)‐resistant breast neoplasm cell line MCF‐7/DOX as well as the mechanism of RES underlying the DOX‐resistant breast cancer. CCK‐8 assay was utilized to assess the survival rates and sensitivity of breast neoplasm cell lines MCF‐7 or MDA‐MB‐231 to DOX and RES. DOX‐resistant MCF‐7 cell line was successfully cultivated with DOX dose increasing and was named MCF‐7/DOX....