Host defense against oral microbiota by bone-damaging T cells
Abstract
The immune system evolved to efficiently eradicate invading bacteria and terminate inflammation through balancing inflammatory and regulatory T-cell responses. In autoimmune arthritis, pathogenic TH17 cells induce bone destruction and autoimmune inflammation. However, whether a beneficial function of T-cell-induced bone damage exists is unclear. Here, we show that bone-damaging T cells have a critical function in the eradication of bacteria in a...
Paper Details
Title
Host defense against oral microbiota by bone-damaging T cells
Published Date
Feb 16, 2018
Journal
Volume
9
Issue
1
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Notes
History