RNF4 regulates zebrafish granulopoiesis through the DNMT1‐C/EBPα axis
Abstract
RING finger protein 4 (RNF4) is a multifunctional small ubiquitin-related modifier (SUMO)-targeted ubiquitin E3 ligase (STUbL) ubiquitously expressed in all tissues, and which mainly participates in DNA repair and in chromatin and transcriptional regulation. Although RNF4 has been implicated in hematopoietic disorders, its ontogenic role during hematopoietic development remains undiscovered. We generated a zebrafish rnf4 knockout line by using...
Paper Details
Title
RNF4 regulates zebrafish granulopoiesis through the DNMT1‐C/EBPα axis
Published Date
Apr 10, 2018
Journal
Volume
32
Issue
9
Pages
4930 - 4940
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