Original paper
Astaxanthin prevents the methotrexate-induced reproductive toxicity by targeting oxidative stress in male mice
Abstract
The future fertility of cancer patients after treatment is a serious concern amongst young cancer patients. Such chemotherapeutic agents as Methotrexate (MTX), a folic acid antagonist can cause long-term or permanent gonadal toxicity in male patients. Oxidative stress is a contributing mechanism to MTX-induced testicular damage. In the past decade, several studies have investigated the use of natural antioxidant agents to prevent the side...
Paper Details
Title
Astaxanthin prevents the methotrexate-induced reproductive toxicity by targeting oxidative stress in male mice
Published Date
Apr 12, 2018
Journal
Volume
38
Issue
3
Pages
248 - 254
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Notes
History