Integration of risk factors for Parkinson disease in 2 large longitudinal cohorts

To prospectively examine how selected lifestyle factors and family history of Parkinson disease (PD) combine to determine overall PD risk.We derived risk scores among 69,968 women in the Nurses' Health Study (NHS) (1984-2012) and 45,830 men in the Health Professionals Follow-up Study (HPFS) (1986-2012). Risk scores were computed for each individual based on the following factors previously associated with PD risk: total caffeine intake, smoking,...