In situ formation of interpenetrating polymer network using sequential thermal and click crosslinking for enhanced retention of transplanted cells
Abstract
Injectable hydrogels, which are used as scaffolds in cell therapy, provide a minimally invasive strategy to enhance cell retention and survival at injection site. However, till now, slow in situ gelation, undesired mechanical properties, and weak cell adhesion characteristics of reported hydrogels, have led to improper results. Here, we developed an injectable fully-interpenetrated polymer network (f-IPN) by integration of Diels-Alder (DA)...
Paper Details
Title
In situ formation of interpenetrating polymer network using sequential thermal and click crosslinking for enhanced retention of transplanted cells
Published Date
Jul 1, 2018
Journal
Volume
170
Pages
12 - 25
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