Is a vegetarian diet safe to follow during pregnancy? A systematic review and meta-analysis of observational studies
Published on Apr 5, 2018in Critical Reviews in Food Science and Nutrition6.70
· DOI :10.1080/10408398.2018.1461062
ABSTRACTBackground: Whether a vegetarian diet is appropriate for pregnancy remains unclear.Objective: This study aimed to determine the association between vegetarian diet during pregnancy and various maternal–fetal outcomes.Method: PubMed-Medline, EMBASE, and Cochrane Library databases were searched for relevant articles published by August 30, 2017. Quantitative data were analyzed by a random-effects model with pooled odds ratios or weighted mean difference (WMD) and 95% confidence interval as aggregate estimations.Results: A total of 19 observational studies were identified for each of meta-analysis and narrative review. The overall estimated relation between vegetarian pregnancy and low birth weight (LBW) was marginally significant (1.27 (0.98, 1.65), P = 0.07, I2 = 0%). Asian (India/Nepal) vegetarian mothers exhibited increased risks to deliver a baby with LBW (1.33 (1.01, 1.76), P = 0.04, I2 = 0%). However, the WMD of neonatal birth weight in five studies suggested no difference between vegetarians ...