N -(3-oxododecanoyl)- l -homoserine lactone modulates mitochondrial function and suppresses proliferation in intestinal goblet cells

Volume: 201, Pages: 81 - 88
Published: May 1, 2018
Abstract
The quorum-sensing molecule N‑(3‑oxododecanoyl)‑l‑homoserine lactone (C12-HSL), produced by the Gram negative human pathogenic bacterium Pseudomonas aeruginosa, modulates mammalian cell behavior. Our previous findings suggested that C12-HSL rapidly decreases viability and induces apoptosis in LS174T goblet cells.In this study, the effects of 100 μM C12-HSL on mitochondrial function and cell proliferation in LS174T cells treated for 4 h were...
Paper Details
Title
N -(3-oxododecanoyl)- l -homoserine lactone modulates mitochondrial function and suppresses proliferation in intestinal goblet cells
Published Date
May 1, 2018
Volume
201
Pages
81 - 88
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