Increased Plasma Levels of Donor-derived Cell-free DNA Correlate With Acute Rejection in the Recipients of Living Donor-lobar Lung Transplantation

Circulating donor-derived cell-free DNA (dd-cf-DNA) has been shown to be an informative biomarker of rejection after lung transplantation from deceased donors. However, in living-donor lobar lung transplantation (LDLLT), because small grafts are implanted with short ischemic time from blood-relatives, the detection of dd-cf-DNA might be challenging, and the role of dd-cf-DNA in the LDLLT recipients remains unknown. Our study was aimed at...