Cortactin recruits FMNL2 to promote actin polymerization and endosome motility in invadopodia formation
Abstract
Recently, invadopodia have been increasingly recognized as important drivers of local invasion and metastasis. Cortactin, as an actin-binding protein, is closely associated with invadopodia through interacting with proteins. Formin-like 2 (FMNL2), a member of diaphanous-related formins which act as nucleation factors, plays an important role in tumor progression. But whether cortactin can interact with FMNL2 to promote invadopodia formation and...
Paper Details
Title
Cortactin recruits FMNL2 to promote actin polymerization and endosome motility in invadopodia formation
Published Date
Apr 1, 2018
Journal
Volume
419
Pages
245 - 256
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