Prosarcopenic Effects of Statins May Limit Their Effectiveness in Patients with Heart Failure

Statins have many ancillary actions that may be relevant for body wasting. Some statin-associated muscle symptoms and sarcopenia mechanisms correspond in HF patients. In HF patients without cachexia, statins may favorably affect the outcomes. Some studies using small doses of statins revealed significant benefits for patients with chronic heart failure (HF). However, the results of large randomized studies did not confirm these advantages. Along...