Intravenous administration of retinoic acid-loaded polymeric nanoparticles prevents ischemic injury in the immature brain

Volume: 673, Pages: 116 - 121
Published: Apr 1, 2018
Abstract
Perinatal stroke is often difficult to diagnose and an established treatment has not yet been validated, except for symptomatic measures. Herein, we propose to test the neuroprotective potential of the intravenous injection of retinoic acid-loaded nanoparticles (RA-NP) upon ischemic injury to the immature brain. The role of RA-NP on endothelial cells and organotypic slice cultures exposed to oxygen and glucose deprivation was assessed by...
Paper Details
Title
Intravenous administration of retinoic acid-loaded polymeric nanoparticles prevents ischemic injury in the immature brain
Published Date
Apr 1, 2018
Volume
673
Pages
116 - 121
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