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Recent advancements in DNA interaction studies of organotin(IV) complexes

Published on May 1, 2018in Inorganic Chemistry Communications1.79
· DOI :10.1016/j.inoche.2018.03.012
Jai Devi6
Estimated H-index: 6
(Guru Jambheshwar University of Science and Technology),
Sushila Pachwania1
Estimated H-index: 1
(Guru Jambheshwar University of Science and Technology)
Abstract
Abstract DNA interaction studies of organotin(IV) complexes have got tremendous attention during the recent years due to their anticancer and antitumor properties. Most of the chemotherapeutic organotins are DNA-targeted as they recognize specific DNA sequences, alter the local DNA structure, inhibit access to the activator or repressor protein and ultimately affect the gene expression process. The binding ability of organotin(IV) compounds with DNA depends on the coordination number and the nature of organic group attached to the central tin atom. In this review, articles available from 2005 onwards have been summarized to get the latest update on the development of organotin compounds having interaction with DNA for understanding the molecular mechanism of drug action and development of new robust DNA-targeted chemotherapeutic drugs.
  • References (114)
  • Citations (7)
References114
Newest
#1Susobhan Mahanty (NITC: National Institute of Technology Calicut)H-Index: 1
#2Darpan Raghav (NITC: National Institute of Technology Calicut)H-Index: 5
Last.Krishnan Rathinasamy (NITC: National Institute of Technology Calicut)H-Index: 5
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#1Shufang Zhang (Qufu Normal University)H-Index: 1
#2Hongyu Yuan (ECUST: East China University of Science and Technology)H-Index: 1
Last.Laijin Tian (Qufu Normal University)H-Index: 2
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#1Jai Devi (Guru Jambheshwar University of Science and Technology)H-Index: 6
#2Suman Devi (Guru Jambheshwar University of Science and Technology)H-Index: 4
Last.Ashwani Kumar (Guru Jambheshwar University of Science and Technology)H-Index: 14
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#1Sabiha Parveen (AMU: Aligarh Muslim University)H-Index: 4
#2Sartaj Tabassum (AMU: Aligarh Muslim University)H-Index: 26
Last.Farukh Arjmand (AMU: Aligarh Muslim University)H-Index: 29
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Cited By7
Newest
#1Jai Devi (Guru Jambheshwar University of Science and Technology)H-Index: 6
#2Suman Devi (Guru Jambheshwar University of Science and Technology)H-Index: 4
Last.Ashwani Kumar (Guru Jambheshwar University of Science and Technology)H-Index: 14
view all 4 authors...
#1Alexandr V. Piskunov (RAS: Russian Academy of Sciences)H-Index: 15
#2O. Yu. Trofimova (RAS: Russian Academy of Sciences)H-Index: 2
Last.Anton V. Cherkasov (RAS: Russian Academy of Sciences)H-Index: 21
view all 4 authors...
#1J. Devi (Guru Jambheshwar University of Science and Technology)H-Index: 1
#2M. Yadav (Guru Jambheshwar University of Science and Technology)H-Index: 1
Last.Deepak Kumar Jindal (Guru Jambheshwar University of Science and Technology)H-Index: 4
view all 5 authors...
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