Association of impaired endothelial glycocalyx with arterial stiffness, coronary microcirculatory dysfunction, and abnormal myocardial deformation in untreated hypertensives

We investigated the association of endothelial glycocalyx damage with arterial stiffness, impairment of coronary microcirculatory function, and LV myocardial deformation in 320 untreated hypertensives and 160 controls. We measured perfused boundary region ( PBR ) of the sublingual microvessels, a marker inversely related with glycocalyx thickness, coronary flow reserve ( CFR ), and Global Longitudinal strain ( GLS ) by echocardiography, pulse...