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Whole blood omega-3 fatty acid concentrations are inversely associated with blood pressure in young, healthy adults

Published on Jul 1, 2018in Journal of Hypertension4.209
· DOI :10.1097/HJH.0000000000001728
Mark G. Filipovic2
Estimated H-index: 2
,
Stefanie Aeschbacher13
Estimated H-index: 13
+ 10 AuthorsJuerg H. Beer7
Estimated H-index: 7
Abstract
Background:Omega-3 fatty acids (n − 3 FA) may have blood pressure (BP)-lowering effects in untreated hypertensive and elderly patients. The effect of n − 3 FA on BP in young, healthy adults remains unknown. The Omega-3 Index reliably reflects an individuals’ omega-3 status. We hypothesized that the
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201623.05Circulation
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#1Clemens von Schacky (LMU: Ludwig Maximilian University of Munich)H-Index: 30
The omega-3 index, the percentage of EPA plus DHA in erythrocytes (measured by standardised analysis), represents a human body's status in EPA and DHA. An omega-3 index is measured in many laboratories around the world; however, even small differences in analytical methods entail large differences in results. Nevertheless, results are frequently related to the target range of 8-11 %, defined for the original and scientifically validated method (HS-Omega-3 Index(R)), raising ethical issues, and c...
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#1Xinping Li (HUST: Huazhong University of Science and Technology)H-Index: 2
#2Yichao Huang (JNU: Jinan University)
Last. Yuanyuan Li (HUST: Huazhong University of Science and Technology)H-Index: 33
view all 13 authors...
Circulating saturated fatty acids (SFAs) have been associated with cardiovascular disease. However, little is known about the relationship of SFAs with the risk of pregnancy-induced hypertension (PIH). We conducted a nested case–control study to examine the associations between circulating SFAs and the risk of PIH. A total of 92 PIH cases were matched to 184 controls by age (±2 years) and infant sex from a birth cohort study conducted in Wuhan, China. Levels of circulating fatty acids in plasma ...
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#1C. von Schacky (LMU: Ludwig Maximilian University of Munich)H-Index: 13
Hintergrund Uber die Wirkungen von Omega-3-Fettsauren herrscht Verwirrung. Wissenschaftliche Untersuchungen brachten scheinbar keine Klarheit. Leitlinien und Regulierungsbehorden widersprechen einander.
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#1William S. Harris (USD: University of South Dakota)H-Index: 77
view all 6 authors...
Abstract Background The Omega-3 Index (O3I; erythrocyte EPA+DHA as a percent of total fatty acids) is inversely related to risk for cardiovascular disease (CVD). The cardioprotective target O3I is 8%–12%. O3I levels in American regions with high CVD risk are poorly characterized. Purpose To determine the O3I in individuals participating in a Seafood Nutrition Partnership (SNP) survey in seven US cities in the CVD “belt.” Methods Fingerstick blood samples were analyzed for the O3I. Results The SN...
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#1Robert Hudek (Rhön-Klinikum)H-Index: 5
#2Clemens von SchackyH-Index: 30
Last. Frank Gohlke (Rhön-Klinikum)H-Index: 28
view all 6 authors...
Abstract Background : The etiology of degenerative rotator cuff tears is multifactorial but chronic inflammation plays an important role in the pathogenesis. Some polyunsaturated fatty acids (PUFA) can modulate inflammation and marine n-3 (Omega-3) PUFA have anti-inflammatory effects. We hypothesized that the Omega-3 Index is lower in patients with degenerative rotator cuff tears when compared to controls without rotator cuff tendinopathy. Methods : From 684 consecutive patients with full thickn...
1 CitationsSource
#1Kayla R Zehr (UNM: University of New Mexico)H-Index: 1
#2Allison Segovia (UNM: University of New Mexico)
Last. Mary K. Walker (UNM: University of New Mexico)H-Index: 28
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Summary Epidemiology studies and clinical trials have shown that omega-3 polyunsaturated fatty acids (n-3 PUFAs) are inversely associated with blood pressure. We sought to determine the influence of cigarette smoking and Hispanic ethnicity on this association. Age- and sex-matched smokers and nonsmokers (n = 98) 19–50 years old lacking cardiovascular disease were recruited. Systolic and diastolic blood pressure (SBP, DBP), heart rate, HbA1c, lipids, BMI, and RBC fatty acids were measured. The om...
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#1Steven HirshH-Index: 2
#2Marianne PonsH-Index: 1
Last. Andrew G. SwickH-Index: 2
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This pilot randomised controlled study evaluated the effects of a nutrient-supported intermittent energy restriction nutrition programme to prevent weight gain in healthy overweight adults during the 6-week winter holiday period between Thanksgiving and New Year. For 52 d, twenty-two overweight adults (mean age 41·0 years, BMI 27·3 kg/m 2 ) were assigned to either the nutrition programme ( n 10; two fasting days of 730 kcal/d (3050 kJ/d) of balanced shake and dietary supplements to support weigh...
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#1Eric P. Davidson (UI: University of Iowa)H-Index: 26
#2Lawrence J. Coppey (UI: University of Iowa)H-Index: 29
Last. Mark A. Yorek (UI: University of Iowa)H-Index: 41
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In this study, we wanted to extend our investigation of the efficacy of fish oil with or without salsalate on vascular and neural complications using a type 2 diabetic rat model. Four weeks after the onset of hyperglycemia, diabetic rats were treated via the diet with 3 different amounts of menhaden oil with or without salsalate for 12 weeks. Afterwards, vascular reactivity of epineurial arterioles and neuropathy-related endpoints were examined. The addition of salsalate to high-fat diets enrich...
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