Review paper

Targeted Nitric Oxide Synthase Inhibitors for Migraine

Volume: 15, Issue: 2, Pages: 391 - 401
Published: Apr 1, 2018
Abstract
Nitric oxide (NO) is a small gaseous signaling molecule that has important biological effects. It has been heavily implicated in migraine; and the NO donor, nitroglycerin, has been used extensively as a human migraine trigger. Correspondingly, a number of components of the NO signaling cascade have been shown to be upregulated in migraine patients. NO is endogenously produced in the body by NO synthase (NOS), of which there are three isoforms:...
Paper Details
Title
Targeted Nitric Oxide Synthase Inhibitors for Migraine
Published Date
Apr 1, 2018
Volume
15
Issue
2
Pages
391 - 401
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