Remodeling of dermal collagen in photoaged skin using low‐dose 5‐aminolevulinic acid photodynamic therapy occurs via the transforming growth factor‐β pathway
Abstract
5‐Aminolevulinic acid photodynamic therapy (ALA‐PDT) is known to be effective in the treatment of photoaged skin. However, the molecular mechanisms still remain elusive. Protoporphyrin IX (PpIX) fluorescence is primarily located in the epidermis while ALA‐PDT affects the dermal collagen, presumably by an indirect mechanism. This study aimed to investigate the molecular communication in low‐dose ALA‐PDT occurring between epidermal keratinocytes...
Paper Details
Title
Remodeling of dermal collagen in photoaged skin using low‐dose 5‐aminolevulinic acid photodynamic therapy occurs via the transforming growth factor‐β pathway
Published Date
Mar 12, 2018
Journal
Volume
11
Issue
6
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