Serine integrase recombinational engineering (SIRE): A versatile toolbox for genome editing

Volume: 116, Issue: 2, Pages: 364 - 374
Published: Nov 15, 2018
Abstract
Chromosomal integration of biosynthetic pathways for the biotechnological production of high‐value chemicals is a necessity to develop industrial strains with a high long‐term stability and a low production variability. However, the introduction of multiple transcription units into the microbial genome remains a difficult task. Despite recent advances, current methodologies are either laborious or efficiencies highly fluctuate depending on the...
Paper Details
Title
Serine integrase recombinational engineering (SIRE): A versatile toolbox for genome editing
Published Date
Nov 15, 2018
Volume
116
Issue
2
Pages
364 - 374
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