Characterization of acetylated histidine b₁-ion structure: A competition between oxazolone and side chain imidazole moiety

The detection of post-translational modifications of proteins is an important comprehensive research area. Over the years, proteomic studies involving protein acetylation have attracted a great deal of attention. In the present study, we have focussed on the acetylation of histidine and the intrinsic stability of b 1 -ion of oxazolone ring and/or with side chain imidazole bicyclic product. The formation of oxazolone structure may occur when an...