Peptide Immunotherapy for Type 1 Diabetes—Clinical Advances

Autoimmune and allergic diseases occur when an individual mounts an inappropriate immune response to a self-antigen, or an innocuous environmental antigen. This triggers a pathogenic T cell response resulting in damage to specific tissues and organs. In type one diabetes this manifests as destruction of the insulin-secreting  cells, resulting in a life-long dependency on recombinant insulin. Modulation of the pathogenic T cell response with...