TGF-b1 or hypoxia enhance glucose metabolism and lactate production via HIF1A signaling in tendon cells
Abstract
Purpose/Aim of the study: Healthy tendons are maintained in homeostasis through controlled usage of glucose for energy and redox equilibrium. Tendon cell stress imposed by overuse injury or vascular insufficiency is accompanied by activation of wound healing pathways which facilitate an adaptive response and the restoration of homeostasis. To understand this response at the gene expression level we have studied the in vivo effects of injected...
Paper Details
Title
TGF-b1 or hypoxia enhance glucose metabolism and lactate production via HIF1A signaling in tendon cells
Published Date
Jun 6, 2018
Journal
Volume
59
Issue
5
Pages
458 - 471
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Notes
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